ATPCL;chm

Lifespan changes: From wild type to ATPCL;chm DF = decrease in function; IF = increase in function

There is no network for this step.
Fullscreen mode
Hide graph
Legend

Genetic mutants with ATPCL, chm alterations

    Names of genes are ordered alphabetically. For the order of interventions, please see the specific paper.
  • Strain

    P{PZ}ATPCL[01446];chm[14]

  • Temperature °C

    25

  • Diet

    water, 1.2% agar, 1.8% yeast, 1% soja, 2.2% sugar syrup, 8% corn extract, 8% malt extract, 0.24% Nipagin, and 6.25 ul/l of propionic acid and yeast extra powder

  • Lifespan (days)

    54.0

  • Lifespan comparisons

    Double mutant ATPCL(DF);chm(DF) has a lifespan of 54.0 days, while single mutant ATPCL(DF) has a lifespan of 57.0 days.

  • Citation
    View abstract

    Peleg S et al., 2016, Life span extension by targeting a link between metabolism and histone acetylation in Drosophila. EMBO Rep. 17(3):455-69 PubMed 26781291 Click here to select all mutants from this PubMed ID in the graph

Search genes: ATPCL chm
  • Entrez ID
  • Symbol
  • GenAge
  • FlyBase ID

ATP citrate lyase


Locus: Dmel_CG8322


  • Entrez ID
  • Symbol
  • GenAge
  • FlyBase ID

chameau


Locus: Dmel_CG5229


Orthologs of ATPCL;chm in SynergyAge
Show in SynergyAge
Species Gene
Orthologs of ATPCL in SynergyAge
Show in SynergyAge
Species Gene
Orthologs of chm in SynergyAge
Show in SynergyAge
Species Gene
About

SynergyAge database hosts high-quality, manually curated information about the synergistic and antagonistic lifespan effects of genetic interventions in model organisms, also allowing users to explore the longevity relationships between genes in a visual way.

Read more about SynergyAge database

Contact
Computational Biology of Aging Group
Institute of Biochemistry, Ground floor
Splaiul Independentei 296, Bucharest, Romania

www.aging-research.group