Trx-2;TrxT

Lifespan changes: From wild type to Trx-2;TrxT DF = decrease in function; IF = increase in function

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Genetic mutants with Trx-2, TrxT alterations

    Names of genes are ordered alphabetically. For the order of interventions, please see the specific paper.
  • Strain

    Trx-2[36];TrxT[J5]

  • Temperature °C

    25

  • Lifespan (days)

    46.9

  • Lifespan change (compared to wild type)

    -7.68%

  • Phenotype

    The TrxT- mutant (w Df(1)J5) had very similar lifespans to the control and the double mutant had only a slightly shorter lifespan than the single TrxT mutant.

  • Lifespan comparisons

    Double mutant Trx-2(DF);TrxT(DF) has a lifespan of 46.9 days, while single mutant TrxT(DF) has a lifespan of 50.4 days, single mutant Trx-2(DF) has a lifespan of 38.4 days and wild type has a lifespan of 50.8 days.

  • Type of interaction
    See methods

    Dependent

  • Citation
    View abstract

    Svensson MJ, Larsson J, 2007, Thioredoxin-2 affects lifespan and oxidative stress in Drosophila. Hereditas. 144(1):25-32 PubMed 17567437 Click here to select all mutants from this PubMed ID in the graph

Search genes: Trx-2 TrxT
  • Entrez ID
  • Symbol
  • GenAge
  • FlyBase ID

thioredoxin-2


Locus: Dmel_CG31884


  • Entrez ID
  • Symbol
  • GenAge
  • FlyBase ID

Thioredoxin T


Locus: Dmel_CG3315


Orthologs of Trx-2;TrxT in SynergyAge
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Species Gene
Orthologs of Trx-2 in SynergyAge
Show in SynergyAge
Species Gene
Orthologs of TrxT in SynergyAge
Show in SynergyAge
Species Gene
About

SynergyAge database hosts high-quality, manually curated information about the synergistic and antagonistic lifespan effects of genetic interventions in model organisms, also allowing users to explore the longevity relationships between genes in a visual way.

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Computational Biology of Aging Group
Institute of Biochemistry, Ground floor
Splaiul Independentei 296, Bucharest, Romania

www.aging-research.group