Sod1;Sod1

Lifespan changes: From wild type to Sod1;Sod1 DF = decrease in function; IF = increase in function

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Genetic mutants with Sod1, Sod1 alterations

    Names of genes are ordered alphabetically. For the order of interventions, please see the specific paper.
  • Strain

    Sod1[1];Sod[X39]

  • Temperature °C

    25

  • Diet

    standard corn meal medium

  • Lifespan (days)

    7.5

  • Lifespan comparisons

    Double mutant Sod1(DF);Sod1(DF) has a lifespan of 7.5 days, while single mutant Sod1(DF) has a lifespan of 7.0 days and single mutant Sod1(DF) has a lifespan of 10.5 days.

  • Citation
    View abstract

    Ruan H, Wu CF, 2008, Social interaction-mediated lifespan extension of Drosophila Cu/Zn superoxide dismutase mutants. Proc Natl Acad Sci U S A. 105(21):7506-10 PubMed 18508973 Click here to select all mutants from this PubMed ID in the graph

  • Strain

    Sod1[1];Sod[X39]

  • Temperature °C

    25

  • Diet

    standard corn meal medium

  • Lifespan (days)

    21.0

  • Phenotype

    Cohousing with w helpers conferred lifespan extension for the various Sod alleles and heteroallelic combinations.

  • Lifespan comparisons

    Double mutant Sod1(DF);Sod1(DF) has a lifespan of 21.0 days, while single mutant Sod1(DF) has a lifespan of 13.5 days and single mutant Sod1(DF) has a lifespan of 21.0 days.

  • Citation
    View abstract

    Ruan H, Wu CF, 2008, Social interaction-mediated lifespan extension of Drosophila Cu/Zn superoxide dismutase mutants. Proc Natl Acad Sci U S A. 105(21):7506-10 PubMed 18508973 Click here to select all mutants from this PubMed ID in the graph

  • Strain

    Sod1[n1];Sod[n64]

  • Temperature °C

    23

  • Diet

    standard corn meal medium

  • Lifespan (days)

    3.5

  • Lifespan comparisons

    Double mutant Sod1(DF);Sod1(DF) has a lifespan of 3.5 days, while single mutant Sod1(DF) has a lifespan of 10.5 days.

  • Citation
    View abstract

    Ruan H, Wu CF, 2008, Social interaction-mediated lifespan extension of Drosophila Cu/Zn superoxide dismutase mutants. Proc Natl Acad Sci U S A. 105(21):7506-10 PubMed 18508973 Click here to select all mutants from this PubMed ID in the graph

  • Strain

    Sod1[n1];Sod[n64]

  • Temperature °C

    23

  • Diet

    standard corn meal medium

  • Lifespan (days)

    16.5

  • Lifespan comparisons

    Double mutant Sod1(DF);Sod1(DF) has a lifespan of 16.5 days, while single mutant Sod1(DF) has a lifespan of 21.0 days.

  • Citation
    View abstract

    Ruan H, Wu CF, 2008, Social interaction-mediated lifespan extension of Drosophila Cu/Zn superoxide dismutase mutants. Proc Natl Acad Sci U S A. 105(21):7506-10 PubMed 18508973 Click here to select all mutants from this PubMed ID in the graph

  • Strain

    Sod[X39];Sod[n64]

  • Temperature °C

    23

  • Diet

    standard corn meal medium

  • Lifespan (days)

    1.5

  • Lifespan comparisons

    Double mutant Sod1(DF);Sod1(DF) has a lifespan of 1.5 days, while single mutant Sod1(DF) has a lifespan of 7.0 days.

  • Citation
    View abstract

    Ruan H, Wu CF, 2008, Social interaction-mediated lifespan extension of Drosophila Cu/Zn superoxide dismutase mutants. Proc Natl Acad Sci U S A. 105(21):7506-10 PubMed 18508973 Click here to select all mutants from this PubMed ID in the graph

  • Strain

    Sod[X39];Sod[n64]

  • Temperature °C

    23

  • Diet

    standard corn meal medium

  • Lifespan (days)

    7.5

  • Lifespan comparisons

    Double mutant Sod1(DF);Sod1(DF) has a lifespan of 7.5 days, while single mutant Sod1(DF) has a lifespan of 13.5 days.

  • Citation
    View abstract

    Ruan H, Wu CF, 2008, Social interaction-mediated lifespan extension of Drosophila Cu/Zn superoxide dismutase mutants. Proc Natl Acad Sci U S A. 105(21):7506-10 PubMed 18508973 Click here to select all mutants from this PubMed ID in the graph

Search genes: Sod1 Sod1
  • Entrez ID
  • Symbol
  • GenAge
  • FlyBase ID

Superoxide dismutase 1


Locus: Dmel_CG11793


  • Entrez ID
  • Symbol
  • GenAge
  • FlyBase ID

Superoxide dismutase 1


Locus: Dmel_CG11793


Orthologs of Sod1;Sod1 in SynergyAge
Show in SynergyAge
Species Gene
Caenorhabditis elegans sod-1;sod-5
Orthologs of Sod1 in SynergyAge
Show in SynergyAge
Species Gene
Caenorhabditis elegans sod-1
Caenorhabditis elegans sod-5
Mus musculus Sod1
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SynergyAge database hosts high-quality, manually curated information about the synergistic and antagonistic lifespan effects of genetic interventions in model organisms, also allowing users to explore the longevity relationships between genes in a visual way.

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Computational Biology of Aging Group
Institute of Biochemistry, Ground floor
Splaiul Independentei 296, Bucharest, Romania

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