sun;y

Lifespan changes: From wild type to sun;y DF = decrease in function; IF = increase in function

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Genetic mutants with sun, y alterations

    Names of genes are ordered alphabetically. For the order of interventions, please see the specific paper.
  • Strain

    sun[EM67];yw[67c23]

  • Temperature °C

    25

  • Diet

    standard cornmeal and agar medium

  • Lifespan (days)

    64.0

  • Lifespan change (compared to wild type)

    60.00%

  • Phenotype

    The increase in lifespan of sun mutants was observed in sun EM67 in w/yw 67c23.

  • Lifespan comparisons

    Double mutant sun(DF);y(IF) has a lifespan of 64.0 days, while single mutant y(IF) has a lifespan of 56.0 days, single mutant sun(DF) has a lifespan of 50.0 days and wild type has a lifespan of 40.0 days.

  • Type of interaction
    See methods

    Almost additive (positive)

  • Citation
    View abstract

    Cvejic S et al., 2004, The endogenous ligand Stunted of the GPCR Methuselah extends lifespan in Drosophila. Nat Cell Biol. 6(6):540-6 PubMed 15133470 Click here to select all mutants from this PubMed ID in the graph

    Names of genes are ordered alphabetically. For the order of interventions, please see the specific paper.
  • Strain

    P{11.6-[3']-S/S};yw[67c23]

  • Temperature °C

    25

  • Diet

    standard cornmeal and agar medium

  • Lifespan (days)

    49.6

  • Lifespan change (compared to wild type)

    24.00%

  • Phenotype

    w /yw 67c23 ; +/pW8gDmM-Sal(3 ' ) female progeny were used to examine whether additional copies of the sun gene could by itself affect the lifespan of Drosophila. An increase in lifespan was not observed in other heterozygotes, such as pW8gDmM-Sal(3 ' ) in w/yw 67c23.

  • Lifespan comparisons

    Double mutant sun(IF);y(IF) has a lifespan of 49.6 days, while single mutant y(IF) has a lifespan of 56.0 days and wild type has a lifespan of 40.0 days.

  • Type of interaction
    See methods

    Contains dependence

  • Citation
    View abstract

    Cvejic S et al., 2004, The endogenous ligand Stunted of the GPCR Methuselah extends lifespan in Drosophila. Nat Cell Biol. 6(6):540-6 PubMed 15133470 Click here to select all mutants from this PubMed ID in the graph

Search genes: sun y
  • Entrez ID
  • Symbol
  • GenAge
  • FlyBase ID

stunted


Locus: Dmel_CG9032


  • Entrez ID
  • Symbol
  • GenAge
  • FlyBase ID

yellow


Locus: Dmel_CG3757


Orthologs of sun;y in SynergyAge
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Species Gene
Orthologs of sun in SynergyAge
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Species Gene
Orthologs of y in SynergyAge
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Species Gene
About

SynergyAge database hosts high-quality, manually curated information about the synergistic and antagonistic lifespan effects of genetic interventions in model organisms, also allowing users to explore the longevity relationships between genes in a visual way.

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Computational Biology of Aging Group
Institute of Biochemistry, Ground floor
Splaiul Independentei 296, Bucharest, Romania

www.aging-research.group