snz;snz

Lifespan changes: From wild type to snz;snz DF = decrease in function; IF = increase in function

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Genetic mutants with snz, snz alterations

    Names of genes are ordered alphabetically. For the order of interventions, please see the specific paper.
  • Strain

    snz[C32];snz[5-SZ-4089]

  • Temperature °C

    22-23

  • Diet

    standard food

  • Lifespan (days)

    77.6

  • Lifespan change (compared to wild type)

    86.54%

  • Phenotype

    Complementation tests with females, the X-chromosome location of snz precluded this analysis in males, and observed lifespan extension in transheterozygotes of C32 with either G1409 or SZ4089.

  • Lifespan comparisons

    Double mutant snz();snz(if) has a lifespan of 77.6 days, while single mutant snz() has a lifespan of 63.2 days, single mutant snz(if) has a lifespan of 73.6 days and wild type has a lifespan of 41.6 days.

  • Type of interaction
    See methods

    Almost additive (positive)

  • Citation
    View abstract

    Suh JM et al., 2008, An RGS-containing sorting nexin controls Drosophila lifespan. PLoS One. 3(5):e2152 PubMed 18478054 Click here to select all mutants from this PubMed ID in the graph

  • Strain

    snz[C32];snz[GG1409];

  • Temperature °C

    22-23

  • Diet

    standard food

  • Lifespan (days)

    95.2

  • Lifespan change (compared to wild type)

    133.33%

  • Phenotype

    Complementation tests with females, the X-chromosome location of snz precluded this analysis in males, and observed lifespan extension in transheterozygotes of C32 with either G1409 or SZ4089.

  • Lifespan comparisons

    Double mutant snz();snz(if) has a lifespan of 95.2 days, while single mutant snz() has a lifespan of 63.2 days, single mutant snz(if) has a lifespan of 73.6 days and wild type has a lifespan of 40.8 days.

  • Type of interaction
    See methods

    Almost additive (positive)

  • Citation
    View abstract

    Suh JM et al., 2008, An RGS-containing sorting nexin controls Drosophila lifespan. PLoS One. 3(5):e2152 PubMed 18478054 Click here to select all mutants from this PubMed ID in the graph

Search genes: snz snz
  • Entrez ID
  • Symbol
  • GenAge
  • FlyBase ID

snazarus


Locus: Dmel_CG1514


  • Entrez ID
  • Symbol
  • GenAge
  • FlyBase ID

snazarus


Locus: Dmel_CG1514


Orthologs of snz;snz in SynergyAge
Show in SynergyAge
Species Gene
Orthologs of snz in SynergyAge
Show in SynergyAge
Species Gene
About

SynergyAge database hosts high-quality, manually curated information about the synergistic and antagonistic lifespan effects of genetic interventions in model organisms, also allowing users to explore the longevity relationships between genes in a visual way.

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Contact
Computational Biology of Aging Group
Institute of Biochemistry, Ground floor
Splaiul Independentei 296, Bucharest, Romania

www.aging-research.group