bax;Ku70

Lifespan changes: From wild type to bax;Ku70

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Genetic mutants with bax, Ku70 alterations

    Names of genes are ordered alphabetically. For the order of interventions, please see the specific paper.
  • Lifespan (days)

    262.5

  • Lifespan change (compared to wild type)

    -65.91%

  • Lifespan comparisons

    Double mutant bax(KO);ku70(KO) has a lifespan of 262.5 days, while single mutant ku70(KO) has a lifespan of 182.0 days and wild type has a lifespan of 770.0 days.

  • Type of interaction
    See methods

    Contains dependence

  • Citation
    View abstract

    Ngo J et al., 2015, Bax deficiency extends the survival of Ku70 knockout mice that develop lung and heart diseases. Cell Death Dis. 6:e1706 PubMed 25811803 Click here to select all mutants from this PubMed ID in the graph

  • Lifespan (days)

    266.0

  • Lifespan change (compared to wild type)

    -65.45%

  • Lifespan comparisons

    Double mutant bax(KO);ku70(KO) has a lifespan of 266.0 days, while single mutant ku70(KO) has a lifespan of 182.0 days and wild type has a lifespan of 770.0 days.

  • Type of interaction
    See methods

    Contains dependence

  • Citation
    View abstract

    Ngo J et al., 2015, Bax deficiency extends the survival of Ku70 knockout mice that develop lung and heart diseases. Cell Death Dis. 6:e1706 PubMed 25811803 Click here to select all mutants from this PubMed ID in the graph

  • Lifespan (days)

    217.0

  • Lifespan change (compared to wild type)

    -71.82%

  • Lifespan comparisons

    Double mutant bax(KO);ku70(KO) has a lifespan of 217.0 days, while single mutant ku70(KO) has a lifespan of 182.0 days and wild type has a lifespan of 770.0 days.

  • Type of interaction
    See methods

    Contains dependence

  • Citation
    View abstract

    Ngo J et al., 2015, Bax deficiency extends the survival of Ku70 knockout mice that develop lung and heart diseases. Cell Death Dis. 6:e1706 PubMed 25811803 Click here to select all mutants from this PubMed ID in the graph

  • Lifespan (days)

    304.5

  • Lifespan change (compared to wild type)

    -60.45%

  • Lifespan comparisons

    Double mutant bax(KO);ku70(KO) has a lifespan of 304.5 days, while single mutant ku70(KO) has a lifespan of 147.0 days and wild type has a lifespan of 770.0 days.

  • Type of interaction
    See methods

    Contains dependence

  • Citation
    View abstract

    Ngo J et al., 2015, Bax deficiency extends the survival of Ku70 knockout mice that develop lung and heart diseases. Cell Death Dis. 6:e1706 PubMed 25811803 Click here to select all mutants from this PubMed ID in the graph

  • Lifespan (days)

    224.0

  • Lifespan change (compared to wild type)

    -70.91%

  • Lifespan comparisons

    Double mutant bax(KO);ku70(KO) has a lifespan of 224.0 days, while single mutant ku70(KO) has a lifespan of 182.0 days and wild type has a lifespan of 770.0 days.

  • Type of interaction
    See methods

    Contains dependence

  • Citation
    View abstract

    Ngo J et al., 2015, Bax deficiency extends the survival of Ku70 knockout mice that develop lung and heart diseases. Cell Death Dis. 6:e1706 PubMed 25811803 Click here to select all mutants from this PubMed ID in the graph

  • Lifespan (days)

    308.0

  • Lifespan change (compared to wild type)

    -60.00%

  • Lifespan comparisons

    Double mutant bax(KO);ku70(KO) has a lifespan of 308.0 days, while single mutant ku70(KO) has a lifespan of 147.0 days and wild type has a lifespan of 770.0 days.

  • Type of interaction
    See methods

    Contains dependence

  • Citation
    View abstract

    Ngo J et al., 2015, Bax deficiency extends the survival of Ku70 knockout mice that develop lung and heart diseases. Cell Death Dis. 6:e1706 PubMed 25811803 Click here to select all mutants from this PubMed ID in the graph

Search genes: bax Ku70
  • Symbol
  • GenAge

No gene information for bax


  • Symbol
  • GenAge

No gene information for Ku70


Orthologs of bax;Ku70 in SynergyAge
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Species Gene
Orthologs of bax in SynergyAge
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Species Gene
Orthologs of Ku70 in SynergyAge
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Species Gene
About

SynergyAge database hosts high-quality, manually curated information about the synergistic and antagonistic lifespan effects of genetic interventions in model organisms, also allowing users to explore the longevity relationships between genes in a visual way.

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Computational Biology of Aging Group
Institute of Biochemistry, Ground floor
Splaiul Independentei 296, Bucharest, Romania

www.aging-research.group